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AGEs may also promote vascular dysfunction by reducing the bioavailability of nitric oxide (NO) and inhibiting endothelial NO synthase and antioxidant defense mechanisms 13,14

Eight to twelve weeks old male and female mice were fed with either a chow or HFD (Research Diets Inc, #D12492) for four months

That part is fairly straightforward

Acknowledgements We owe our thanks to Jialin Yu for his work on revising in this manuscript

Inflammation and resolution in tissue healing

Conditional Growth Model Parameter Estimates: Executive Function Figure 6 depicts final multivariate growth curve models including all TICs and TVCs for neuropsychological test performance for all measures between the first through fifth annual follow-ups