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Another mysterious but not altogether unpleasant side effect, according to study participants, involved spontaneous penile erection in men who had previously been diagnosed with ED, or erectile dysfunction

In the Dorr study, three healthy male subjects were subcutaneously administered 0.01 mg/kg of MT-II daily for two consecutive weeks, with one, two, or all three experiencing [5]: Somnolence Fatigue Nausea Stretching Yawning Spontaneous penile erections According to the Wessells et al

The injection form was tested and refined in women (leading to the 2019 FDA approval for HSDD), but what about men

Better circulation, better sleep, and better mood often follow

This is because ice crystal formation can disrupt the peptide structure, potentially leading to loss of biological activity or altered properties

These fluctuations don't invalidate the 28-day window, but they do mean that a vial stored in a standard home refrigerator is experiencing slightly accelerated degradation compared to a pharmaceutical-grade cold storage unit