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doi: 10.2147/ijn.S344679 280 AhmedATaitSWG

Silberg, D

5.982.29 log 10 copies/mL), and proportion with a lifetime alcohol intake of more than 292 kg (30.8% vs

As mentioned earlier, this might be explained by the fact that CAR and PXR share many binding partners and target genes, suggesting that they could compensate for each others activities upon inhibition, as reflected by the upregulation of several CAR target genes upon CLP or HNF4 depletion in the liver (57, 58)