L-ascorbic acid inhibits breast cancer growth by inducing IRE/JNK/CHOP-related endoplasmic reticulum stress-mediated p62/SQSTM1 accumulation in the nucleus
doi: 10.1128/MCB.00894-10 319 Mota de SPRichardAJHangHStephensJM
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The importance and specificity of all SOD isoforms originate from their diverse cellular locations, which maintain the redox state of cellular compartments within physiological limits, ensuring homeostasis and cell survival
3 The relationship between obesity and genetic predisposition, as well as genes related to airway remodeling The potential association between obesity and airway remodeling, particularly concerning genetic predisposition, is a subject of consideration
It is possible that the observed actions occurred through a complex signaling mechanism that involves the PI3K (Phosphoinositide 3-kinases) and AMPK (AMP-activated protein kinase) pathways