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Indeed, in both studies, the highest frequency of TEAEs was in the normal function groups, possibly owing to the smaller sample sizes in the more severe impairment groups, or alternatively because participants with more serious health concerns, such as those with severe renal or hepatic impairment, may be less likely to notice or report mild or moderate TEAEs, as observed in populations with cancer [21]

To validate the feasibility of our AD-related pathway-gene network-based method for identifying natural products for AD, we conducted a thorough search of PubMed, Web of Science, and Scopus to determine the research status of the 177 natural products

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Activation of the pY397 autophosphorylation site of FAK promotes SRC binding, leading to the conformational activation of SRC, and, subsequently, a dual activated FAKSRC signalling complex (Mitra et al, 2005)