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Some people may initially notice: Fatigue Weakness Low energy Difficulty concentrating Mood changes As deficiency progresses, symptoms may become more noticeable

Because MTHFR gene variations impair the bodys ability to convert B vitamins, methylated forms of B vitamins are considered the most bioavailable as they dont need any conversion by the body Consider high doses: you might need significant doses of methylcobalamin to treat a deficiency

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