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Even if the main folate receptors are blocked by antibodies, leucovorin can enter the central nervous system through the reduced folate carrier (RFC) , essentially bypassing the roadblock at the FR [4]

By neutralizing lipid peroxides via the enzyme Glutathione Peroxidase 4 (GPx4), L-glutathione preserves the structural integrity of the mitochondrial membrane, allowing the ETC to resume efficient ATP production

In one of these studies, Mishra et al

M., Van Houtte, J