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Claims of specific target engagement based on such assays alone are highly speculative

[DOI] [PubMed] [Google Scholar] 39.Wee AK, Sultana R

Importantly, this work provides, to our knowledge, the first fully specified, step-by-step description of a Peyronies disease management protocol, enabling reproducible clinical implementation and facilitating meaningful comparison across future studies employing different biologic agents

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These findings support the notion that targeting lipid metabolic dysfunction may offer a feasible strategy to mitigate CaOx crystal-induced kidney damage