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These implied the translocation of cytoplasmic ACSL4 into mitochondria during the pathogenic process of MASH

To determine the point at which mitochondrial Fe-S protein function is compromised by cystine starvation, we assessed respiratory complex activity in cells subject to cystine deprivation for 096 h that were concomitantly treated with ferrostatin-1 to prevent the induction of ferroptosis

Synthesis, characterization, antibacterial, antifungal and cytotoxic activity of curcuminoid analogues with trisubstituted phenyl and anthracenyl ring and their zinc (II), copper (II) and vanadyl (IV) chelates

M.SivanjineyuluV.JayaramuduJ.VaraprasadK.SadikuE

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Indeed, APR-246 was synergistic with GPX4 inhibitor, ML-210, in parental OVCAR5 and SKOV3 (Fig