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Activation of the farnesoid X receptor (FXR), a ligandactivated nuclear hormone receptor that is a key regulator of bile acid homeostasis, has demonstrated clinical benefit in patients with PSC, as shown by the sustained reduction in serum alkaline phosphatase levels induced by multiple FXR agonists, including obeticholic acid in a phase 2 trial (NCT02177136)

Astaxanthin Zeaxanthin is a type of carotenoid thats found in abundance in your eyes

The pharmacological action of disulfiram (DSF) is attributed to the inhibition of acetaldehyde metabolism by aldehyde dehydrogenase (ALDH) in the liver 2,3

To investigate the impact of ITCs on S

Asparagine bioavailability governs metastasis in a model of breast cancer

These findings are in line with previous studies, further confirming the association between CKD and retinal lesions, while uncovering the potential mechanisms of ferroptosis in retinal degeneration, offering new insights to the existing literature and expanding the pathological research on retinal lesions