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Clinical Study Results (REDEFINE) Cagrilintide is a long-acting amylin analogue: Monotherapy: In REDEFINE-1, cagrilintide monotherapy was associated with approximately 11.8% weight loss

This progress indicates that it may be possible to use this approach for transplantation purposes in the future

The K m values of the Y398A variant toward tyrosine and DOPA are 5- and 2-fold higher than that of the WT enzyme, respectively

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