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Conversely, excessive Cu can generate OH via the Fenton reaction, inducing oxidative stress and cellular damage [97]

To adjust for multiple comparisons post-hoc , the Benjamini-Hochberg procedure was used since it provides better statistical power than the Bonferroni correction [25]

Formal analysis : AB, LGN, DM, SB and VG

Due to their heterogeneity, astrocytes play a plethora of roles in stroke progression, which makes it impossible to simply classify them as good or bad. Research on astrocyte biology has gained momentum in recent years, and several astrocytic molecular targets with therapeutic potential have been identified in the context of ischemic stroke (Table 1)

Funding This work was partially supported by COST EMF-MED Action (BM1309), European network for innovative uses of EMFs in biomedical applications

Nat Immunol