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The NO pathway plays an important role in intestinal smooth muscle function and mucosal protection, and disruption of this system is associated with certain inflammatory bowel presentations

We applied this LC-MS platform to ~10,000 mutants and sequenced over 300 mutants with significant phenotypes

Notably, ectopic endometrial lesions show this pattern of respiratory hyperactivation, with increased levels of Complex I and cytochrome b, along with elevated matrix expression of ATP, SOD2, and ROS