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Description

Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity

doi: 10.3389/fnmol.2016.00053 31

This is believed to be linked to the potent antioxidant abilities of L-Glutathione, as free radicals contribute to age-related changes and the deterioration of brain health

10.3389/fphar.2022.860492 52 HillK

A study by Mendes et al (77) demonstrated that ~50% of tested patients with HCU showed defective SAM activation, often linked to specific CBS mutations

These observations collectively underscore the role of various iron-dependent enzymes, including ALOX and POR, in promoting lipid peroxidation and ferroptosis