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406,407,408 A phase 2 RCT demonstrated that berberine ursodeoxycholate significantly reduced liver fat content, improved glycemic control, lowered liver enzyme levels, and promoted weight loss in T2D patients with presumed NASH

J Mol Cell Cardiol 125:185194 Zhong J, Tan Y, Lu J, Liu J, Xiao X, Zhu P et al (2019) Therapeutic contribution of melatonin to the treatment of septic cardiomyopathy: a novel mechanism linking Ripk3-modified mitochondrial performance and Endoplasmic reticulum function