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Originally only described for the reduction of GSH-mixed disulfides, the monothiol reaction mechanism may also be functional for the reduction of certain protein disulfides, e.g., mammalian RNR and engineered GFP variants [36,37]

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(2) Plasma-membrane lipid bilayer: ROS attacks membrane PUFAs, driving lipid peroxidation and generating cytotoxic aldehydes such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), which compromise membrane integrity and fluidity and impair motility/fertilization-related functions

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Tanner CM, Kamel F, Ross GW, Hoppin JA, Goldman SM, Korell M, et al

MRI is the standard neuroimaging technique used to measure brain injury and a study by N Bhroin et al