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It was found that the t 1/2 time of schisandrin in female rats was prolonged by two times, and the C max value was also increased by 20 times (63)

R 3 is a D or L isoleucine, leucine or valine amino acid residue n ranges from 3-6

Cirrhosis is characterized by liver damage and fibrosis, the primary causes of liver fibrosis/cirrhosis include HBV and HCV infections, nonalcoholic steatohepatitis, and alcoholism, with an increasing incidence of HCV and alcoholism

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These positive effects were mainly achieved by affecting sucrose, starch, and amylose contents, i.e., by spermidines transcriptional regulation of carbohydrate metabolism-related enzymes

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