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A series of studies have shown that miR-155 plays a crucial role in ALD [40]

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Moreover, infiltrating T cells upregulate Nox4 in the inflammatory microenvironment and produce a large number of extracellular ROS, such that they themselves undergo ferroptosis, thereby weakening immune surveillance

Additionally, older adults who naturally have a more challenging time absorbing vitamin B12 or those on certain medications that affect B12 absorption may be ideal candidates

Delving into these regulatory mechanisms might pave the way for innovative therapeutic interventions, diagnostics, or preventive measures, especially in those conditions where dysregulation of Sb9 is a key factor

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