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Similarly, patients who experience other symptoms or signs suggestive of decreased arterial flow, such as ischemic bowel syndrome or Raynaud's syndrome following the use of any 5-HT agonist are candidates for further evaluation (see WARNINGS)

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A friend of mine accidentally dosed it too high and was groggy for two days straight. Best Time to Take DSIP (Delta-Sleep Inducing Peptide) The ideal time to use DSIP is 1 to 3 hours prior to sleep to ensure maximum efficacy after kicking in