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WT mice were unilaterally injected with AAV- hSyn - SNCA or - GPX4 into the substantia nigra as described above to obtain strains overexpress human -synuclein, GPX4, or both

Methods This international panel of multidisciplinary experts in the management and/or study of CCA, including physicians and clinical researchers (oncologists, surgeons, hepatologists, gastroenterologists and pathologists), basic and translational scientists, and patient representatives, is affiliated with the European Network for the Study of Cholangiocarcinoma (ENS-CCA) and is part of the European COST Actions Euro-Cholangio-Net (20192023) and Precision-BTC-Network (20232027)

Hernndez-Fonseca JP, Rincn J, Pedreaez A, Viera N, Arcaya JL, Carrizo E

Steatosis prevalence ranged from 36.2-49.6% and varied by sociodemographic and clinical factors (Fig 1A)

When activated, Siglec-8 curtails eosinophil survival and functionthereby regulating ROS output and preventing excessive collateral damage

Padil, M