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When cells are exposed to increased levels of oxidative stress, GSSG accumulates and the ratio of GSH/GSSG decreases to ratios as low as 10:1 and even 1:1

It has to distinguished that the replacement therapy should be only undertaken to restore the physiological levels, never to exceed physiological ranges

These authenticators can be provided by either the RP (as in Sec

the most abundant phospholipid in mammalian cells) was elevated in the kidneys of vehicle-treated mice (Figure 5E)

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Nitrous oxide, a commonly used anesthetic, oxidizes and inactivates vitamin B 12 , thus inhibiting both of the vitamin B 12 -dependent enzymes, and can produce many of the clinical features of vitamin B 12 deficiency, such as megaloblastic anemia and neuropathy