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hCAC is represented as space fill model from AlphaFold prediction As such, endogenous synthesis and reabsorption may be more relevant for homeostasis

trimethylamine is efficiently absorbed and metabolized to trimethylamine- N -oxide, which is excreted in the urine (13)

However, reduction of HOMA-IR between groups was not significantly different (LC vs

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Genetic sequencing is not solely a research tool for CVS but is employed on a daily basis by the Corresponding Author in the clinical management of the condition in his patients, generally involving WGS as it also includes useful information in the mtDNA sequence, genetic architecture (large rearrangements), and pharmacogenomic variants (e.g., in dosing amitriptyline)