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Further investigation should be performed to elucidate its mechanism of action on brain morphometry [138]

Bacteroides fragilis enterotoxin cleaves the zonula adherens protein, E-cadherin

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Together, this framework enables a comprehensive assessment of disease status, identification of vulnerable or high-risk phenotypes, and implementation of risk-adapted management strategies

However, CB-839 in combination with other agents targeting multiple mechanisms may provide an additional strategy to overcome the metabolic adaptations in CLL

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