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Ceftriaxone for injection is contraindicated in neonates ( 28 days) if they require (or are expected to require) treatment with calcium-containing IV solutions, including continuous calcium-containing infusions such as parenteral nutrition because of the risk of precipitation of ceftriaxone-calcium (see CLINICAL PHARMACOLOGY, WARNINGS and DOSAGE AND ADMINISTRATION)

Moreover, the combined expression of E2 and E1 proteins from HR-HPV18 triggers even higher levels of OS and DNA damage compared to E2 alone

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45 Because this study had no control group it is impossible to establish whether the observed benefits were due to a placebo effect

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