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Particularly important for mitochondrial fitness is the role of mGSH in the regulation of ATP production

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Concato-LopesVMSilvaTFDetoniMBCruzEMSGonalvesMDda Silva BortoletiBTet al3,3,5,5-Tetramethoxybiphenyl-4,4diol triggers oxidative stress, metabolic changes, and apoptosis-like process by reducing the PI3K/AKT/NF-B pathway in the NCI-H460 lung cancer cell line

NAD+ enhances cellular resistance to oxidative stress by increasing -GCL, a key enzyme for glutathione synthesis