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Heme is an important inhibitor of BACH2, which represses transcription of Blimp-1 138

These data prompted us to test whether increasing the antioxidant levels through dietary -lipoic acid would relieve oxidative stress in the DBA/2J mouse model of chronic glaucoma

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12 weeks (~8 vials): ~24 mL 3 bottles 12 weeks (~12 vials): ~36 mL 4 bottles Alcohol Swabs One for the vial stopper + one for the injection site each session

Plan to wait at least 30-45 minutes after injection before consuming food

The ensuing phagocytosis of RBCs may lead to iron overload within macrophages, which has been shown to cause progressive macrophage dysfunction, inflammatory M1 polarization, increased ferroptosis and exacerbated atherosclerosis 66,67,68,69,70,71