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Chronic low-grade inflammation, increasingly recognized as a contributor to numerous age-related health conditions, may be partially mediated by inadequate antioxidant defenses including suboptimal glutathione status

Unter bestimmten Bedingungen, wie metabolischem Stress, reicht die Eigensynthese allerdings nicht aus

however, it contains no glutamatergic neurons

50,63,60 Vitamin E considerably lowers oxidative and nitrosative damage in AD

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During the propagative phase, molecular oxygen reacts with phospholipid radicals rapidly, leading to the formation of phospholipid peroxy radicals (PLOO)