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To examine the potential role of Erk1/2 as an MR-dependent stress signal linked to the ISR in HepG2 cells, we tested whether MR affected Erk1/2 activity and whether inhibition of Erk1/2 impaired MR-dependent induction of ISR genes

Concluding Remarks In this review, we covered the basic components for designing colorimetric sensing systems, typical examples of POC devices, recent exciting sensing techniques based on combinational and activatable systems up to 2023, and challenges and future perspectives

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