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This indicated that the autophagy level of T-BPH rat prostates was relatively elevated and could be further aggravated by ferroptosis inducer (RSL3), while the up-regulation of GPX3 expression (TRO treatment) could significantly antagonize autophagy induced by T or RSL3

doi: 10.3390/biom11030440

A novel CD133- and EpCAM-targeted liposome with redox-responsive properties capable of synergistically eliminating liver cancer stem cells

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Bass C, Puinean AM, Zimmer CT, Denholm I, Field LM, Foster SP

Mitochondrial function is required for extracellular ATP-induced NLRP3= inflammasome activation