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Controlled and uncontrolled studies using folinic acid, a reduced form of folate, have reported marked improvements in core and associated ASD symptoms in some children with ASD and folate related pathway abnormities

Furthermore, ROS can induce additional loss of membrane potential by activating the mPTP, ultimately triggering cell apoptosis

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Lv Q-K, Tao K-X, Wang X-B, Yao X-Y, Pang M-Z, Liu J-Y, et al

Given the critical role of HMOs in the development and antioxidant capacity of the intestinal flora, more forward-looking, thorough clinical research is needed to evaluate the association between HMOs and BPD

Table 3 Therapeutic strategies targeting microglial ferroptosis