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This observation aligns with the rationale that RSL3 is a drug that inhibits GPX4 and thus, enhances the sensitivity of cells to ferroptosis

5.3.3 Synbiotics Synbiotics, a mixture containing live microorganisms and substrate(s) selectively utilized by host microorganisms that confer health benefits on the host (Swanson et al., 2020), have been employed to improve the diversity and richness of a dysbiotic gut, favor saccharolytic metabolism, reduce serum levels of free IS, improve intestinal permeability and alleviate constipation (Celano et al., 2023

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