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Without a sterile environment and specialized equipment, it is highly likely that your homemade solution will contain bacteria

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doi: 10.1371/journal.pone.0126185 106 HillmannF.NovohradskS.MatternD

Using 13 C-labelled yeast extracts as a normalization strategy establishes a paradigm in quantitative MSI-based spatial metabolomics that greatly enhances reliability and interpretive strength