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Functional CFTR is located on the apical membrane of epithelial cells, where it conducts chloride and bicarbonate ions towards the extracellular space

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In contrast to LDL, high-density lipoprotein (HDL) inhibits the expression of surface markers and inflammation-related genes such as TNF-, IL-6, and monocyte chemotactic protein-1 (MCP-1) in macrophages, reducing the production of ROS and RNS and blocking the polarization of macrophages toward the M1 type (175)

doi: 10.1158/2159-8290.CD-20-1453 86 ZhaoSLiPWuWWangQQianBLiXet al

We developed composition-based models using best-selected features/compositions (four type of residues) and got maximum R/R 2 of 0.61/0.35 with MAE 1.42 (Table 2, Additional file 1: Table S1)

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