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In cardiomyocytes, the intermediate GSH:GSSG ratios may cause reversible mitochondrial m, while strongly decreased ratios can cause irreversible PTP activation (Aon et al

IL-5-induced OXPHOS and glycolysis in eosinophils is signal transducer and activator of transcription 5 (STAT5) and phosphoinositide 3-kinase (PI3K)/Akt-dependent, with STAT5 and PI3K driving both OXPHOS and glycolysis, whilst Akt contributing only to glycolytic activation

Salonia A et al

But another large trial didn't find any difference

Optimizing delivery systems remains a challenge, despite advances in formulation technology, to overcome biological barriers while maintaining EGCGs stability [122]