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Several recent reports have shown that the microbial metabolite TMAO influences colorectal carcinogenesis

Colonic transit time is a driven force of the gut microbiota composition and metabolism: in vitro evidence

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P = 0.91

In addition to its weight management benefits, it can positively impact exercise recovery and muscle fatigue

These animals are viable and fertile, so we largely used them to identify SMA genetic modifiers through candidate 50,51,52,53 and unbiased genetic screenings 54,55 , or to find modifying compounds that partially prevent neuronal death 56 , including valproic acid, which was successfully used in other models of SMA 18,27,57