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Signs of low vitamin B12 include: Fatigue Nausea Throwing up Diarrhea Losing weight without trying A sore tongue A yellow tinge to your skin Fuzzy thinking Numbness or tingling in your hands and feet Vision changes Trouble walking or speaking Feeling easily irritated Confusion Depression Many conditions share these same symptoms

This localized malabsorption can lead to a functional B12 deficiency, even if dietary intake appears adequate

Their willingness to participate in this case report has significantly contributed to the advancement of medical knowledge

All studies have been conducted using 80 g4 mg/kg/day and ranging in a wide spectrum of lengths (weeks to months) and routes of administration

2.2.1 Inclusion criteria Healthy adults, male or female, aged 1865 years Stable medical conditions, including stable hepatic, renal and hematological status confirmed by the laboratory tests