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Similar content being viewed by others Background Human lung structure evolves to facilitate O 2 -CO 2 exchange in the alveolar-capillary unit, where microvascular endothelium, interstitium, and alveolar epithelium form an intact alveolar-capillary membrane (ACM) as a selective barrier to prevent protein-rich fluid diffusion and non-gaseous solute passage (Fig

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POLG-related disorders and their neurological manifestations