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This induces the activation of microglia and astrocytes, which in turn aggravates neurodegenerative damage and drives the progression of Alzheimers disease (AD) (Wang et al., 2023)

Modifications to these proteins affect different processes in the cell such as the activation/inactivation of transcription, chromosome packaging, DNA damage and DNA repair

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Lack of SMARCA4 inhibits expression of the aldehyde dehydrogenase ALDH16A1 that binds to the Trx1 active site and inhibits its function but also promotes lysosomal degradation of the redoxin [95]

The combined effect supports better blood sugar control and may reduce appetite

Studies have shown that higher vitamin E intake was associated with lower total cholesterol and LDL cholesterol levels, and with higher HDL cholesterol levels