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Alzheimers disease ( AD ) is the most common neurodegenerative disease and the leading cause of dementia in the elderly population (101)

At a pH above the pI, a protein will have a net negative charge, while a pH below the pI will lead to a net positive charge

Bone disorders associated with diabetes mellitus and its treatments

The adopted approach led to the identification of 138 research articles, of which 81 studies (58.7%) focused on DNA methylation as a diagnostic cancer biomarker, whereas the remaining 57 studies (41.3%) explored the potential of methylation hotspots as cancer-specific prognostic biomarkers

The authors demonstrated that inhibition of acetylation of Mfn2 by sirtuin or overexpression of Mfn2 reduced mitochondrial fragmentation and enhanced the removal of damaged mitochondria (Alka et al., 2023)