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Niacin also offers therapeutic benefits to patients with AD, PD, HD, MS, and schizophrenia by combating OS, redox imbalance, and mitochondrial dysfunction [123,127]

doi:10.1016/j.freeradbiomed.2016.02.028

Differential diagnosis For other causes of 5-oxoprolinuria, besides 5-oxoprolinase deficiency and glutathione synthetase deficiency [9, 29], please see Table 1

Hypoxia-inducible factor 2 (HIF-2) was shown to significantly influence cartilage formation, the development of OA, and cellular resistance to ferritin [83]

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