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Studies showed that the GHK-Cu sequence was found in collagen and was thought to be released, as a collagen degradation product, in response to tissue injury

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Its hair-relevant evidence is largely mechanistic and indirect, drawn from the same properties documented in its extensive skin and wound-healing literature VEGF upregulation, angiogenesis, anti-inflammatory and antioxidant effects, stimulation of fibroblasts and extracellular-matrix synthesis, and broad gene-expression modulation

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