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Likewise, the overexpression of miR-339-5p diminishes ROS production by targeting p66Shc, thereby mitigating I/R-induced damage[144]

Yoshida T, Delafontaine P

This pathway allowed AOD-9604 to be marketed in the United States as a dietary supplement without the efficacy evidence required for a New Drug Application (NDA)

-3 supplementation has been shown to attenuate neuroinflammation, regulate neurotransmitter biosynthesis, and enhance neurotrophic factor expression, ultimately improving emotional regulation and social interaction in children with ASD (Walter et al., 2025)

After allowing for a brief interaction period of 1 min, excess solution was gently blotted away using a piece of filter paper