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Elevated serum zonulin levels, as well as bacterial dysbiosis and a leaky gut barrier, have been observed in patients with rheumatoid arthritis, while subclinical intestinal inflammation has been observed in patients with ankylosing spondylitis [74, 75]

Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimers disease-like phenotypes in a preclinical mouse model

BPC-157 activates the VEGFR2-Akt-eNOS pathway, increasing blood vessel formation by 129% to 152% in damaged tissues according to preclinical studies

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doi: 10.1016/j.molimm.2016.01.008 54 SonDOLiuWLiXPrudhommeGJWangQ