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The reviewer (JZ) declared a shared affiliation with the authors to the handling editor at time of review

Schedule I lists drugs or other substance that have a high potential for abuse have no accepted medical use in the United States, and do not have accepted safety guidelines for use

Research in Proceedings of the Nutrition Society demonstrates that lymphocyte function is exquisitely sensitive to intracellular glutathione levels, with immune cells requiring a delicately balanced intermediate glutathione concentration for optimal performance

2013 Jun

This is a key reason why many current clinical treatment regimens utilize suppositories or enemas

J Trace Elem Med Biol 55:190195