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Metabolism of phosphatidylinositol 4-kinase III--dependent PI4P is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity

As anticipated, we observed a corresponding decrease in both intracellular and secreted PCSK9 protein levels without significant changes in Pcsk9 mRNA expression in hepatocytes lacking Abcc4 (Fig

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Reasons for these discrapencies among studies and between functional assays and molecular tests are not clear