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US Environmental Protection Agency, Washington, DC Modesto KA, Martinez CBR (2010) Roundup causes oxidative stress in liver and inhibits acetylcholinesterase in muscle and brain of the fish Prochilodus lineatus

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The criterion for the classification as a diabetic was based on subjects having glycated haemoglobin (HbA1c) levels 6.5%

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Although their precise mechanisms of action remain to be completely elucidated, it has been reported that HCQ inhibits the mitochondrial antioxidant system induced by TCR crosslinking, consequently increasing mROS levels and reducing CD4+ T cell proliferation through oxidative stress (173)