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bulk organic matter (Fig

doi: 10.1182/blood.2019000200 86 ChenXLinPLuYZhengJLinYZhouZet al

In contrast, CHOP, which is itself transcriptionally upregulated by ATF4, acts as a negative feedback regulator

While diet should certainly be seen as the primary source of nutrients required to protect us against oxidative stress, supplementation can be highly beneficial where diet falls short or when an increased need arises