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Accumulating evidence indicates that ET improves diastolic function, cardiorespiratory fitness, exercise capacity, and quality of life (QoL) in HFpEF patients [76,77,78]

[44], we evaluated the mutual reactions of the H

SCFAs can interact with free fatty acid receptor 3 present on brain endothelial cells (109), suppress inflammatory responses, and alleviate oxidative stress, thereby promoting BBB stability