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In addition, the mechanism of detoxification by GSTD2 was revealed via its strong affinity towards isothiocyanate and catalysis of the conjugation between GSH and isothiocyanate

Lipid peroxidation Polyunsaturated fatty acids (PUFAs), such as adrenoyl (ADA) and arachidonoyl (AA), are the easiest lipids to oxidize in ferroptosis [89]

109 Thus, it is insufficient to simply measure non-specific parameters that could be somewhat associated with ferroptosis and correlate them with injury and protection