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Prior studies have used protein microarrays 19,20 , 2-dimensional electrophoresis (2DE) 12,21,22,23 , and top-down 24 as well as shotgun proteomics 25,26,27 to examine variable sarcoidosis phenotypes including Lofgrens syndrome, non-Lofgrens chest x-ray (CXR) stage I, and stage II/III pulmonary sarcoidosis and compared them to subjects with asthma, IPF, tuberculosis or healthy smoking and non-smoking controls

Ionizable groups pKa values for amino acid side chains are very dependent upon the chemical environment in which they are present

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These results demonstrate that the normal level of TPL/TPR activity is required for BZR1-mediated gene repression and hypocotyl cell elongation

Each peptide delivers a targeted message to one specific system

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